2021, Vol. 3, Issue 1, Part I

Background and Objective: The sudden and prolonged loss of renal function that causes urea, creatinine, and other metabolic wastes to be retained is known as acute renal failure (ARF). The objective of this study is to examine the characteristics, etiology, and outcomes of acute kidney injury (AKI) patients.

Materials and Methods: The study was undertaken at Department of General Medicine, Madha Medical College, Chennai, Tamil Nadu, India as a prospective investigation. After giving their informed consent, participants who met the requirements and visited the medical department throughout the experiment were enrolled in the study.

Results: The age range of the participants was 19 to 87, with an average age of 49.5. The ratio of men to women was 4.84 to 1. Sepsis and malaria infection were the main causes of acute kidney damage (AKI), contributing to 15.8% of cases. Leptospirosis and acute gastroenteritis were also important causes of AKI. Among patients suffering from sepsis and septic shock, 14.5% showed signs of multiple organ failure. Forty people were classified as having stage II AKI in terms of AKIN.

Conclusion: According to the current study, men were more likely than women to have acute kidney injury (AKI), which was identified at a younger age. Severe illness and malaria were the main causes of death. It was frequently discovered that patients with leptospirosis, multiple organ dysfunction syndrome (MODS), and sepsis were in stage III acute kidney injury (AKI). The mortality rate as a whole was 2.76 percent.